Nasolacrimal duct obstruction with ethyl-cyanoacrylate as an adjuvant in the treatment of keratoconjunctivitis sicca in dogs
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Rosa, A. da S., Pereira, J. T., & Botteon, R. de C. C. M. (2012). Nasolacrimal duct obstruction with ethyl-cyanoacrylate as an adjuvant in the treatment of keratoconjunctivitis sicca in dogs. Brazilian Journal of Veterinary Medicine, 34(4), 353–360. Retrieved from https://bjvm.org.br/BJVM/article/view/744

Abstract

ABSTRACT. Rosa A. da S., Pereira J.T. & Botteon R. de C.C.M. [Nasolacrimal duct obstruction with ethyl-cyanoacrylate as an adjuvant in the treatment of keratoconjunctivitis sicca in dogs]. Obstrução do duto nasolacrimal com etil-cianoacrilato como adjuvante no tratamento da ceratoconjuntivite seca em cães. Revista Brasileira de Medicina Veterinária, 34(4):353-360, 2012. Programa de Pós-Graduação em Medicina Veterinária, Universidade Federal do Rio de Janeiro, BR 465, km 07, Seropédica, RJ 23851-900, Brasil. E-mail: dr.telhado@gmail.com Keratoconjunctivitis sicca, a common ocular morbid condition in pets, especially dogs, is characterized by the decrease of the watery portion of tears resulting in dryness and inflammation of the cornea and conjunctiva, ocular discomfort and decreased visual acuity. As an alternative to the use of artificial tears can be used a technique of nasolacrimal duct obstruction in order to increase the retention of tear on the cornea in patients who still had some tear production. Eleven dogs with keratoconjunctivitis sicca (tear production different from 0.0 mm / minute and Jones test positive) were subjected to obstruction of the upper puncta using ethyl-cyanoacrylate as a gel in the eye that showed lower production of aqueous tear while the contra-lateral eye served as control. The obstruction was confirmed by the Jones test. Over five weeks, the animals were evaluated for the presence of obstruction, retention capacity of the tear, and adverse reactions. After 28 days three animals (3 / 11) had mucosal exudate in the treated eye and the Jones test showed up negative for all animals. Regarding side effects, four (4 / 11) had conjunctival injection in the first week and seven had chemosis only in the treated eye immediately after obstruction. The test data of Schirmer tear test were analyzed by single factor ANOVA for repeated measures and data on amount of exudate were analyzed by nonparametric Friedman. From the results we can conclude that the use of ethyl cyanoacrylate in nasolacrimal duct obstruction proved to be a good way to treat keratoconjunctivitis sicca and low cost, thus allowing the treatment.

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