In vitro evaluation of the activity of Cinnamaldehyde as an inhibitor of the biological cycle of Ctenocephalides felis felis
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Keywords

biocontrol, cat flea, natural products.

How to Cite

da Conceição, C. L., Marré, E. O., da Silva’, Y. H., Santos, L. de O., Guimarães, B. G., Monsores e Silva, T., … Coumendouros, K. (2023). In vitro evaluation of the activity of Cinnamaldehyde as an inhibitor of the biological cycle of Ctenocephalides felis felis. Brazilian Journal of Veterinary Medicine, 45, e005123. https://doi.org/10.29374/2527-2179.bjvm005123

Abstract

The objective of this work was to evaluate the in vitro activity of cinnamaldehyde as an inhibitor of the biological cycle of Ctenocephalides felis felis. Tests were carried out with six repetitions containing 10 eggs of C. felis felis together with 0.5g of diet and filter paper discs with area of 23.76 cm2 impregnated with different concentrations of cinnamaldehyde (6; 8; 10; 12; 14; 16; 18; 20; 24 and 28 µg.cm-2) in Petri dishes and incubated in a climate-controlled chamber at 27 ± 1 °C and RH 75 ± 10%, for 30 days. The tests included a placebo group containing the diluent (acetone) and a negative control group, without treatment. At the end of 30 days, the percentage of inhibition of adult emergence/mortality was calculated, as well as the LC 50 and LC90. Inhibition of adult emergence greater than 50% was observed from a concentration of 10 µg.cm-2 and 100% inhibition from a concentration of 14 µg.cm-2, obtaining LC 50 and LC90 results of 8.75 and 13.57 µg.cm-2, respectively. We concluded that the volatile compound cinnamaldehyde is effective in vitro as an inhibitor of the biological cycle of C. felis felis.

https://doi.org/10.29374/2527-2179.bjvm005123
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References

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Copyright (c) 2023 Cecília Lopes da Conceição, Ester Oliozi Marré, Ygor Henrique da Silva', Larissa de Oliveira Santos, Brena Gava Guimarães, Taynara Monsores e Silva, Matheus Eduardo Costa da Silva', Diefrey Ribeiro Campos, Fabio Barbour Scott, Katherina Coumendouros